Nimesh Chahare, PhD

Work

I’m a Postdoctoral Research Scientist at Columbia University, New York with Prof. Nerurkar on understanding mechanics of morphogenesis in chick embryos.

I’m also a founder and convenor of the International Epithelial Mechanics Club, where we are building a community of scientists interested in Epithelial Mechanics and role of mechanical forces in biological contexts.

Interests

My research interests are related to mechanobiology in development.
Combining mechanical engineering and biology, my research explores how physical forces shape embryonic development. From engineering tissues in vitro to studying tissue formation in vivo, I connect continuum mechanics, material science, and tissue engineering.

Projects

Scientific

Artistic

Publications

Patents

Pullarkat, P., Vishwakarma, R., Gundiah, N., and Chahare, N. R., A microscope mountable fluid shear device. Indian patent, IN201641029893A, pg 275/677 Published 2018-03-09.

Articles in Peer-Reviewed Journals

Equal contrubition is indicated by +

Andreu, I. + , Granero-Moya, I. + , Chahare, N. R., Clein, K., Jordàn, M. M., Beedle, A. E., … & Roca-Cusachs, P. (2022). Mechanical force application to the nucleus regulates nucleocytoplasmic transport. Nature Cell Biology

Andreu, I. + , Falcones, B. + , Hurst, S., Chahare, N., Quiroga, X., Le Roux, A. L., … & Roca-Cusachs, P. (2021). The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening. Nature communications, 12(1), 1-12.

Chatterjee, A., Chahare, N. R., Kondaiah, P., & Gundiah, N. (2021). Role of Fiber Orientations in the Mechanics of Bioinspired Fiber-Reinforced Elastomers. Soft Robotics, 8(6), 640-650.

Kundanati, L., Chahare, N. R., Jaddivada, S., Karkisaval, A. G., Sridhar, R., Pugno, N. M., & Gundiah, N. (2020). Cutting mechanics of wood by beetle larval mandibles. Journal of the Mechanical Behavior of Biomedical Materials, 112, 104027.

Conferences

Chahare, N. R., Ouzeri, A., Golde, T., Wilson, T., Roca-cusachs, P., Arroyo, M., and Trepat, X. “ Harnessing active viscoelasticity for synthetic epithelial morphogenesis.” German Physics Society, Dresden, Germany. March 26-31, 2023

Chahare, N. R., Ouzeri, A., Golde, T., Wilson, T. Arroyo, M., and Trepat, X. “Shaping epithelia through buckling in pressure-controlled tissue.” World congress of biomechanics, Taipei, Taiwan. July 10-14, 2022

Chahare, N. R., Ouzeri, A., Golde, T., Wilson, T. Arroyo, M., and Trepat, X. “Synthetic epithelial morphogenesis through controlled stretching and buckling.” EMBL-IBEC Conference, Engineering multicellular systems, Barcelona, Spain. June 08-10, 2022

Chahare, N. R., Ouzeri, A., Golde, T., Wilson, T. Arroyo, M., and Trepat, X. “Synthetic epithelial morphogenesis through controlled stretching and buckling.” EMBO-EMBL Symposium, Mechanobiology in development and disease, Heidelberg, Germany. May 15–18, 2022

Chatterjee, A., Chahare, N. R., Kulkarni, A., Kondaiah, P., and Gundiah, N. “Design of adynamic cell stretcher to quantify responses of fibroblasts to cyclic stretching and TGF-β.”5th International Conference on Computational and Mathematical Biomedical Engineering,Pittsburgh, Pennsylvania, USA. April 10–12, 2017

Satone, V., Chahare, N. R., and Padole, P. “Design of pedal operated behda crackingmachine using flywheel motor.” Association for Machines and Mechanisms’ IndustrialProblems on Machines and Mechanisms (IPRoMM), Nagpur, India. Dec 22–23, 2016

Abhijith, K. G., Chahare, N. R., Kundanati, L., and Gundiah, N. “Mechanics of the Cuticleof Wood Boring Insects.” Structural Integrity Conference and Exhibition (SICE), Bengaluru,India. July 4–6, 2016